#Fatigue
acute is <1mo, subacute 1-6 mo, chronic >6mo
Causes:
Lifestyle: alcohol, chemical dependence, extremes of activity, frequent travel (jet lag), night shift work, work/life imbalance
Medical: anemia, cancer, CKD, chronic liver disease, chronic lung disease, heart failure, HIV/AIDs, hyperglycemia, obesity, thyroid disorders
Medication side effects: antidepressants, antihistamines, antipsychotics, benzodiazepines, beta blockers, opioids
Psychological: anxiety, depression, stress
Sleep: poor sleep habits, restless leg syndrome, sleep apnea, sleep deprivation
Workup: cbc, CMP, tsh, GAD7, PHQ9
#systemic exertion intolerance disease (SEID)
Diagnosis of SEID requires the presence of all of the following three symptoms:
A substantial reduction or impairment in the ability to engage in pre-illness levels of occupational, educational, social, or personal activities that persists for more than 6 months and is accompanied by fatigue, which is often profound, is of new or definite onset (not lifelong), is not the result of ongoing excessive exertion, and is not substantially alleviated by rest
Postexertional malaise
Unrefreshing sleep
In addition, the patient must have at least one of the following two manifestations:
Cognitive impairment
Orthostatic intolerance (symptoms such as lightheadedness, dizziness, and headache that worsen with upright posture and improve with recumbency)